Association between high-normal levels of alanine aminotransferase and risk factors for atherogenesis.

ABSTRACT:

Background & aims

Liver disease has been associated with cardiovascular disorders, but little is known about the relationship between serum levels of alanine aminotransferase (ALT) and markers of atherogenesis. We investigated the relationship between low-normal and high-normal levels of ALT and an extended panel of cardiovascular risk factors among individuals with no known diseases in a primary care setting.

Methods

We performed a retrospective analysis of data collected from 6442 asymptomatic patients at wellness visits to a primary care setting in central Virginia from 2010 through 2011. Serum levels of ALT were compared with levels of lipids and lipoproteins, as well as metabolic, inflammatory, and coagulation-related factors associated with risk for cardiovascular dise

SUBMITTER: Siddiqui MS 

PROVIDER: S-EPMC3840068 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature