Genome-wide comparative analysis of phylogenetic trees: the prokaryotic forest of life.

ABSTRACT: Genome-wide comparison of phylogenetic trees is becoming an increasingly common approach in evolutionary genomics, and a variety of approaches for such comparison have been developed. In this article, we present several methods for comparative analysis of large numbers of phylogenetic trees. To compare phylogenetic trees taking into account the bootstrap support for each internal branch, the Boot-Split Distance (BSD) method is introduced as an extension of the previously developed Split Distance method for tree comparison. The BSD method implements the straightforward idea that comparison of phylogenetic trees can be made more robust by treating tree splits differentially depending on the bootstrap support. Approaches are also introduced for detecting tree-like and net-like evolutionary tr

SUBMITTER: Puigbo P 

PROVIDER: S-EPMC3842619 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature