Estimating EQ-5D and OAB-5D health state utilities for patients with overactive bladder.

ABSTRACT:

Background

Limited utility data on patients suffering from overactive bladder (OAB) are available in the literature. The objectives of this study were to estimate utility values in patients with OAB using the generic EQ-5D questionnaire and the OAB-5D disease specific questionnaire, to investigate the relationship between utilities and symptoms, and to evaluate the sensitivity of the two instruments to changes in symptom severity.

Methods

Analyses were based on pooled data from three large multicenter randomized 12-week placebo-controlled trials (SCORPIO, ARIES, CAPRICORN). Patients completed a micturition diary, EQ-5D and OAB-q (a quality of life questionnaire from which OAB-5D is derived) at baseline and at weeks 4, 8 and 12. Time trade-off tariffs elicited from UK populat

SUBMITTER: Desroziers K 

PROVIDER: S-EPMC3842710 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature