Factors influencing enrollment of African Americans in the Look AHEAD trial.

ABSTRACT:

Background

Many factors have been identified that influence the recruitment of African Americans into clinical trials; however, the influence of eligibility criteria may not be widely appreciated. We used the experience from the Look AHEAD (Action for Health in Diabetes) trial screening process to examine the differential impact eligibility criteria had on the enrollment of African Americans compared to other volunteers.

Methods

Look AHEAD is a large randomized clinical trial to examine whether assignment to an intensive lifestyle intervention designed to produce and maintain weight loss reduces the long-term risk of major cardiovascular events in adults with type 2 diabetes. Differences in the screening, eligibility, and enrollment rates between African Americans and member

SUBMITTER: Mount DL 

PROVIDER: S-EPMC3843916 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature