The Cooperative Lifestyle Intervention Program-II (CLIP-II): design and methods.

ABSTRACT: A complication of cardiovascular disease (CVD) and the metabolic syndrome (MetS) among older adults is loss of mobility. The American Heart Association has identified weight management as a core component of secondary prevention programs for CVD and is an important risk factor for physical disability. The American Society for Nutrition and the Obesity Society have highlighted the need for long-term randomized clinical trials to evaluate the independent and additive effects of diet-induced weight loss (WL) and physical activity in older persons on outcomes such as mobility, muscle function, and obesity related diseases. Here we describe the rationale, design, and methods of a translational study, the Cooperative Lifestyle Intervention Program-II (CLIP-II). CLIP-II will randomize 252 obese,

SUBMITTER: Marsh AP 

PROVIDER: S-EPMC3843993 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature