CD24+/CD38- as new prognostic marker for non-small cell lung cancer.

ABSTRACT:

Background

Lung cancer is the leading cause of death among cancers in the world. The annual death toll due to this disease exceeds the combined deaths caused by colon, breast, prostate, and pancreatic cancers. As a result, there has been a tremendous effort to identify new biomarkers for early detection and diagnosis of lung cancer.

Methods

In this study we report the results of screening a panel of eight non-small cell lung cancer (NSCLC) cell lines originating from different subtypes of lung cancer in an attempt to identify potential biomarkers unique to this disease. We used real-time polymerase chain reaction and flow cytometry techniques to analyze the expression of ALDHA1, EpCAM, CD133, CD24, and CD38 in this panel.

Results

We demonstrate for the first time that

SUBMITTER: Karimi-Busheri F 

PROVIDER: S-EPMC3844723 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature