Joint effects of serum ferritin and body mass index on the risk of coronary artery disease: a case-control study.

ABSTRACT:

Objectives

Serum ferritin and body mass index (BMI) have been reportedly associated with coronary artery disease (CAD) risk. The aim of the present study was to explore the interaction between serum ferritin and BMI on CAD risk.

Design

Hospital-based case-control study.

Setting

Patients with CAD and the controls were recruited from Qilu Hospital, Shandong University.

Participants

258 CAD cases and 282 healthy controls.

Methods

Multiplicative interaction was assessed through a cross-product interaction term in a multivariate logistic regression model. The effect of serum ferritin and BMI were evaluated per 50 µg/L and per 2 kg/m(2), respectively. The presence of additive interaction between serum ferritin and BMI was evaluated by calculation of the relati

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC3845034 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature