Age-dependent decline of association between obesity and coronary heart disease: a cohort study in a remote Australian Aboriginal community.

ABSTRACT:

Objective

To determine whether the association between obesity and coronary heart disease (CHD) in Aboriginal adults depends on age.

Design, setting and participants

A cohort study with up to 20 years of follow-up of 849 participants aged 18-76 years in a remote Aboriginal community in the Northern Territory of Australia.

Main outcome measures

Newly diagnosed CHD cases were identified through hospital records according to ICD codes during the follow-up period. Cox proportional hazard model was used to assess whether the association between obesity and CHD depends on age.

Results

During the follow-up period, 171 participants were diagnosed with CHD. On an average, the incidence rate of CHD increased with the increasing baseline BMI, 11.3%, 16.3% and 20.2% for no

SUBMITTER: Wang Z 

PROVIDER: S-EPMC3845075 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature