Descending necrotizing mediastinitis associated with Lactobacillus plantarum.

ABSTRACT:

Background

Descending necrotizing mediastinitis (DNM), a severe infection with a high fatality rate, develops in mediastinal spaces due mainly to deep cervical abscesses. The majority of causative microbes of DNM are Streptococci and oral anaerobes. DNM associated with Lactobacillus-infection is rather rare.

Case presentation

A 69-year-old male with an unremarkable past medical history was referred to our hospital for surgical resection of advanced laryngeal cancer. Full examination revealed a neck abscess and DNM with a background of untreated diabetes mellitus. Initially, he was treated with meropenem. However, Lactobacillus plantarum was isolated from surgical drainage of a mediastinal abscess. Despite using antibiotics capable of eradicating all isolates with susceptibil

SUBMITTER: Nei T 

PROVIDER: S-EPMC3847138 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature