Severe late-onset multisystem cytomegalovirus infection in a premature neonate previously treated for congenital infection.

ABSTRACT:

Background

Cytomegalovirus is the most common pathogen causing congenital infection and can result in significant neurodevelopmental adverse outcomes. For this reason, it is the standard of care in many regions to treat congenital cytomegalovirus infection involving the brain with six weeks of ganciclovir. There have been no reports in the published literature of significant cytomegalovirus neonatal infection in infants previously treated for congenital infection.

Case presentation

A preterm male infant with congenital symptomatic cytomegalovirus infection was initially treated with over 8 weeks of ganciclovir between the ages of 3 and 14 weeks. At four months chronologic age, just prior to planned discharge, he developed an episode of life-threatening multisystem cytomegalo

SUBMITTER: El-Sayed MF 

PROVIDER: S-EPMC3847698 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature