Association between novel adipocytokines adiponectin, vaspin, visfatin, and thyroid: An experimental and clinical update.

ABSTRACT: Adipose tissue secretes a variety of active biological substances, called adipocytokines, that act in an autocrine, paracrine, and endocrine manner. They have roles in appetite control, thermogenesis, and thyroid and reproductive functions. All these molecules may lead to local and generalized inflammation, mediating obesity-associated vascular disorders including hypertension, diabetes, atherosclerosis, and insulin resistance. Thyroid dysfunction is associated with changes in body weight, thermogenesis, and energy expenditure. The connections between cardiovascular risk factors such as dyslipidemia, impaired glucose tolerance, insulin resistance, atherosclerosis, and thyroid dysfunction have been reported in several studies. The adipocytokines serve as causative or protective factors in t

SUBMITTER: Cinar N 

PROVIDER: S-EPMC3847914 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature