CKD-mineral and bone disorder and risk of death and cardiovascular hospitalization in patients on hemodialysis.

ABSTRACT:

Background and objectives

Parathyroid hormone, calcium, and phosphate have been independently associated with cardiovascular event risk. Because these parameters may be on the same causal pathway and have been proposed as quality measures, an integrated approach to estimating event risks is needed.

Design, setting, participants, & measurements

Prevalent dialysis patients were followed from August 31, 2005 to December 31, 2006. A two-stage modeling approach was used. First, the 16-month probabilities of death and composite end point of death or cardiovascular hospitalization were estimated and adjusted for potential confounders. Second, patients were categorized into 1 of 36 possible phenotypes using average parathyroid hormone, calcium, and phosphate values over a 4-month ba

SUBMITTER: Block GA 

PROVIDER: S-EPMC3848404 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature