Total or Partial Knee Arthroplasty Trial - TOPKAT: study protocol for a randomised controlled trial.

ABSTRACT:

Background

In the majority of patients with osteoarthritis of the knee the disease originates in the medial compartment. There are two fundamentally different approaches to knee replacement for patients with unicompartmental disease: some surgeons feel that it is always best to replace both the knee compartments with a total knee replacement (TKR); whereas others feel it is best to replace just the damaged component of the knee using a partial or unicompartment replacement (UKR). Both interventions are established and well-documented procedures. Little evidence exists to prove the clinical and cost-effectiveness of either management option. This provides an explanation for the high variation in treatment of choice by individual surgeons for the same knee pathology.The aim of the TO

SUBMITTER: Beard D 

PROVIDER: S-EPMC3848560 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature