An easy operating pathogen microarray (EOPM) platform for rapid screening of vertebrate pathogens.

ABSTRACT:

Background

Infectious diseases emerge frequently in China, partly because of its large and highly mobile population. Therefore, a rapid and cost-effective pathogen screening method with broad coverage is required for prevention and control of infectious diseases. The availability of a large number of microbial genome sequences generated by conventional Sanger sequencing and next generation sequencing has enabled the development of a high-throughput high-density microarray platform for rapid large-scale screening of vertebrate pathogens.

Methods

An easy operating pathogen microarray (EOPM) was designed to detect almost all known pathogens and related species based on their genomic sequences. For effective identification of pathogens from EOPM data, a statistical enrichment al

SUBMITTER: Huang W 

PROVIDER: S-EPMC3848773 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature