Different patterns of gene structure divergence following gene duplication in Arabidopsis.

ABSTRACT:

Background

Divergence in gene structure following gene duplication is not well understood. Gene duplication can occur via whole-genome duplication (WGD) and single-gene duplications including tandem, proximal and transposed duplications. Different modes of gene duplication may be associated with different types, levels, and patterns of structural divergence.

Results

In Arabidopsis thaliana, we denote levels of structural divergence between duplicated genes by differences in coding-region lengths and average exon lengths, and the number of insertions/deletions (indels) and maximum indel length in their protein sequence alignment. Among recent duplicates of different modes, transposed duplicates diverge most dramatically in gene structure. In transposed duplications, parental

SUBMITTER: Wang Y 

PROVIDER: S-EPMC3848917 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature