Global insights into energetic and metabolic networks in Rhodobacter sphaeroides.

ABSTRACT:

Background

Improving our understanding of processes at the core of cellular lifestyles can be aided by combining information from genetic analyses, high-throughput experiments and computational predictions.

Results

We combined data and predictions derived from phenotypic, physiological, genetic and computational analyses to dissect the metabolic and energetic networks of the facultative photosynthetic bacterium Rhodobacter sphaeroides. We focused our analysis on pathways crucial to the production and recycling of pyridine nucleotides during aerobic respiratory and anaerobic photosynthetic growth in the presence of an organic electron donor. In particular, we assessed the requirement for NADH/NADPH transhydrogenase enzyme, PntAB during respiratory and photosynthetic growth. U

SUBMITTER: Imam S 

PROVIDER: S-EPMC3849096 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature