Improved estimation of inbreeding and kinship in pigs using optimized SNP panels.

ABSTRACT:

Background

Traditional breeding programs consider an average pairwise kinship between sibs. Based on pedigree information, the relationship matrix is used for genetic evaluations disregarding variation due to Mendelian sampling. Therefore, inbreeding and kinship coefficients are either over or underestimated resulting in reduction of accuracy of genetic evaluations and genetic progress. Single nucleotide polymorphism (SNPs) can be used to estimate pairwise kinship and individual inbreeding more accurately. The aim of this study was to optimize the selection of markers and determine the required number of SNPs for estimation of kinship and inbreeding.

Results

A total of 1,565 animals from three commercial pig populations were analyzed for 28,740 SNPs from the PorcineSNP60 Bea

SUBMITTER: Lopes MS 

PROVIDER: S-EPMC3849284 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature