Identification of neglected cestode Taenia multiceps microRNAs by illumina sequencing and bioinformatic analysis.

ABSTRACT:

Background

Worldwide, but especially in developing countries, coenurosis of sheep and other livestock is caused by Taenia multiceps larvae, and zoonotic infections occur in humans. Infections frequently lead to host death, resulting in huge socioeconomic losses. MicroRNAs (miRNAs) have important roles in the post-transcriptional regulation of a large number of animal genes by imperfectly binding target mRNAs. To date, there have been no reports of miRNAs in T. multiceps.

Results

In this study, we obtained 12.8 million high quality raw reads from adult T. multiceps small RNA library using Illumina sequencing technology. A total of 796 conserved miRNA families (containing 1,006 miRNAs) from 170,888 unique miRNAs were characterized using miRBase (Release 17.0). Here, we selecte

SUBMITTER: Wu X 

PROVIDER: S-EPMC3849562 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature