Positive selection in glycolysis among Australasian stick insects.

ABSTRACT:

Background

The glycolytic pathway is central to cellular energy production. Selection on individual enzymes within glycolysis, particularly phosphoglucose isomerase (Pgi), has been associated with metabolic performance in numerous organisms. Nonetheless, how whole energy-producing pathways evolve to allow organisms to thrive in different environments and adopt new lifestyles remains little explored. The Lanceocercata radiation of Australasian stick insects includes transitions from tropical to temperate climates, lowland to alpine habitats, and winged to wingless forms. This permits a broad investigation to determine which steps within glycolysis and what sites within enzymes are the targets of positive selection. To address these questions we obtained transcript sequences from sev

SUBMITTER: Dunning LT 

PROVIDER: S-EPMC3850572 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature