Modelling the impact of chlamydia screening on the transmission of HIV among men who have sex with men.

ABSTRACT:

Background

Recent studies have found high prevalences of asymptomatic rectal chlamydia among HIV-infected men who have sex with men (MSM). Chlamydia could increase the infectivity of HIV and the susceptibility to HIV infection. We investigate the role of chlamydia in the spread of HIV among MSM and the possible impact of routine chlamydia screening among HIV-infected MSM at HIV treatment centres on the incidence of chlamydia and HIV in the overall MSM population.

Methods

A mathematical model was developed to describe the transmission of HIV and chlamydia among MSM. Parameters relating to sexual behaviour were estimated from data from the Amsterdam Cohort Study among MSM. Uncertainty analysis was carried out for model parameters without confident estimates. The effects of dif

SUBMITTER: Xiridou M 

PROVIDER: S-EPMC3851177 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature