Association between tuberculin skin test result and clinical presentation of tuberculosis disease.

ABSTRACT:

Background

The tuberculin skin test (TST) is used to test for latent tuberculosis (TB) infection and support the diagnosis of active TB. However, little is known about the relationship between the TST result and the clinical presentation of TB disease.

Methods

We analyzed US TB surveillance data, 1993-2010, and used multinomial logistic regression to calculate the association between TST result (0-4 mm [negative], 5-9 mm, 10-14 mm, and  ≥ 15 mm) and clinical presentation of disease (miliary, combined pulmonary and extrapulmonary, extrapulmonary only, non-cavitary pulmonary, and cavitary pulmonary). For persons with pulmonary disease, multivariate logistic regression was used to calculate the odds of having acid-fast bacilli (AFB) positive sputum.

Results

There were 64

SUBMITTER: Auld SC 

PROVIDER: S-EPMC3851915 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature