Comparing cellular performance of Yarrowia lipolytica during growth on glucose and glycerol in submerged cultivations.

ABSTRACT: Yarrowia lipolytica is an attractive host for sustainable bioprocesses due to its ability to utilize a variety of carbon substrates and convert them to a range of different product types (including lipids, organic acids and polyols) under specific conditions. Despite an increasing number of applications for this yeast, relatively few studies have focused on uptake and metabolism of carbon sources, and the metabolic basis for carbon flow to the different products. The focus of this work was quantification of the cellular performance of Y. lipolytica during growth on glycerol, glucose or a mixture of the two. Carbon substrate uptake rate, growth rate, oxygen utilisation (requirement and uptake rate) and polyol yields were estimated in batch cultivations at 1 litre scale. When glucose was use

SUBMITTER: Workman M 

PROVIDER: S-EPMC3852309 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature