Cross-coupling of remote meta-C-H bonds directed by a U-shaped template.

ABSTRACT: meta-C-H arylation and methylation of 3-phenylpropanoic acid and phenolic derivatives were developed using an easily removable nitrile template. The combination of a weakly coordinating U-shaped template and mono-protected amino acid ligand was crucial for the cross-coupling of C-H bonds with organoborons.

SUBMITTER: Wan L 

PROVIDER: S-EPMC3854838 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature