Concordance of effects of medical interventions on hospital admission and readmission rates with effects on mortality.

ABSTRACT:

Background

Many clinical trials examine a composite outcome of admission to hospital and death, or infer a relationship between hospital admission and survival benefit. This assumes concordance of the outcomes "hospital admission" and "death." However, whether the effects of a treatment on hospital admissions and readmissions correlate to its effect on serious outcomes such as death is unknown. We aimed to assess the correlation and concordance of effects of medical interventions on admission rates and mortality.

Methods

We searched the Cochrane Database of Systematic Reviews from its inception to January 2012 (issue 1, 2012) for systematic reviews of treatment comparisons that included meta-analyses for both admission and mortality outcomes. For each meta-analysis, we synth

SUBMITTER: Hemkens LG 

PROVIDER: S-EPMC3855143 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature