Insulin resistance and environmental pollutants: experimental evidence and future perspectives.

ABSTRACT:

Background

The metabolic disruptor hypothesis postulates that environmental pollutants may be risk factors for metabolic diseases. Because insulin resistance is involved in most metabolic diseases and current health care prevention programs predominantly target insulin resistance or risk factors thereof, a critical analysis of the role of pollutants in insulin resistance might be important for future management of metabolic diseases.

Objectives

We aimed to critically review the available information linking pollutant exposure to insulin resistance and to open the discussion on future perspectives for metabolic disruptor identification and prioritization strategies.

Methods

We searched PubMed and Web of Science for experimental studies reporting on linkages between env

SUBMITTER: Hectors TL 

PROVIDER: S-EPMC3855520 | biostudies-literature | 2013 Nov-Dec

REPOSITORIES: biostudies-literature