Uptake and positive predictive value of fecal occult blood tests: A randomized controlled trial.

ABSTRACT:

Objective

The aim of this study is to compare the uptake of three mailed high-sensitivity fecal occult blood tests (FOBTs).

Methods

We conducted a parallel 3-arm randomized controlled trial in an integrated healthcare delivery system in Washington State. From January 2010 through February 2011, automated data were used to identify potentially eligible patients aged 50-74 due for colorectal cancer screening. Participants were mailed one of three FOBT kits (1-sample OC-Auto® fecal immunochemical test [FIT], 2-sample InSure® FIT, or 3-sample guaiac Hemoccult SENSA®), instructions, and a postage-paid return envelope. We performed a modified intent-to-treat analysis with return of any FOBT within 6 months of randomization as the primary outcome.

Results

Of the 9922 people

SUBMITTER: Chubak J 

PROVIDER: S-EPMC3856243 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature