Custodiol for myocardial protection and preservation: a systematic review.

ABSTRACT:

Introduction

Custodiol cardioplegia is attractive for minimally invasive cardiac surgery, as a single dose provides a long period of myocardial protection. Despite widespread use in Europe, there is little data confirming its efficacy compared with conventional (blood or crystalloid) cardioplegia. There is similar enthusiasm for its use in organ preservation for transplant, but also a lack of data. This systematic review aimed to assess the evidence for the efficacy of Custodiol in myocardial protection and as a preservation solution in heart transplant.

Methods

Electronic searches were performed of six databases from inception to October 2013. Reviewers independently identified studies that compared Custodiol with conventional cardioplegia (blood or extracellular crystalloi

SUBMITTER: Edelman JJ 

PROVIDER: S-EPMC3857005 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature