CoCEST: cobalt(II) amide-appended paraCEST MRI contrast agents.

ABSTRACT: The first examples of air-stable Co(II) paraCEST MRI contrast agents are reported. Amide NH protons on the complexes give rise to CEST peaks that are shifted up to 112 ppm from the bulk water resonance. One complex has multiple CEST peaks that may be useful for ratiometric mapping of pH.

SUBMITTER: Dorazio SJ 

PROVIDER: S-EPMC3857136 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature