Meta-analysis of long-term vitamin D supplementation on overall mortality.

ABSTRACT:

Introduction

It has been suggested that vitamin D is effective to prevent mortality. However, there is no consistent conclusion that the effects of vitamin D supplementation on all-cause mortality are associated with duration of treatment. We conducted a meta-analysis regarding this issue in an effort to provide a more robust answer.

Methods

A comprehensive search in a number of databases, including MEDLINE, Embase and The Cochrane Central Register of Controlled Trials, was conducted for collecting randomized controlled trials (RCTs) on vitamin D supplementation preventing mortality. Two investigators independently screened the literature according to the inclusive and exclusive criteria and the relative data were extracted. Data analysis was performed by using Review Manage

SUBMITTER: Zheng Y 

PROVIDER: S-EPMC3857784 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature