Two-dimensional stimulated resonance Raman spectroscopy study of the Trp-cage peptide folding.

ABSTRACT: We report a combined molecular dynamics (MD) and ab initio simulation study of the ultrafast broadband ultraviolet (UV) stimulated resonance Raman (SRR) spectra of the Trp-cage mini protein. Characteristic two dimensional (2D) SRR features of various folding states are identified. Structural fluctuations erode the cross peaks and the correlation between diagonal peaks is a good indicator of the α-helix formation.

SUBMITTER: Ren H 

PROVIDER: S-EPMC3859311 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature