Rectal microbicide development.

ABSTRACT:

Purpose of review

Individuals practicing unprotected receptive anal intercourse are at particularly high risk of HIV infection. Men who have sex with men (MSM) in the developed and developing world continue to have disproportionate and increasing levels of HIV infection. The past few years have seen important progress in demonstrating the efficacy of oral pre-exposure prophylaxis (PrEP), vaginal microbicides, and treatment as prevention, but there has also been significant progress in the development of rectal microbicides. The purpose of this review is to summarize the status of rectal microbicide research and to identify opportunities, challenges, and future directions in this important field of HIV prevention.

Recent findings

Recent phase 1 rectal microbicide studies have

SUBMITTER: McGowan I 

PROVIDER: S-EPMC3861872 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature