Regulation of Endothelial Permeability in the Corpus Luteum: A Review of the Literature.

ABSTRACT: The development of the human corpus luteum (yellow body) is dictated by a strictly controlled system of mutually communicating cells, the luteal steroid hormone-producing cells and endothelial cells. This cell-to-cell communication facilitates control of neoangiogenesis which is a prerequisite for the development of the corpus luteum and its function, the rapid release of large amounts of progesterone into the blood-vascular system. Preconditions for this process are the hormonal regulation of endothelial cell proliferation as well as of vascular permeability through LH and hCG. The morphological correlates of endothelial permeability are cell-to-cell adhesion molecules such as adherens junctions (AJ) and tight junctions (TJ) that open and close the gaps between mutually interacting, neigh

SUBMITTER: Herr D 

PROVIDER: S-EPMC3862051 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature