Perfusion deficits detected by arterial spin-labeling in patients with TIA with negative diffusion and vascular imaging.

ABSTRACT:

Background and purpose

A substantial portion of clinically diagnosed TIA cases is imaging-negative. The purpose of the current study is to determine if arterial spin-labeling is helpful in detecting perfusion abnormalities in patients presenting clinically with TIA.

Materials and methods

Pseudocontinuous arterial spin-labeling with 3D background-suppressed gradient and spin-echo was acquired on 49 patients suspected of TIA within 24 hours of symptom onset. All patients were free of stroke history and had no lesion-specific findings on general MR, DWI, and MRA sequences. The calculated arterial spin-labeling CBF maps were scored from 1-3 on the basis of presence and severity of perfusion disturbance by 3 independent observers blinded to patient history. An age-matched cohort

SUBMITTER: Qiao XJ 

PROVIDER: S-EPMC3864013 | biostudies-literature | 2013 Nov-Dec

REPOSITORIES: biostudies-literature