Pd(0)-catalyzed sequential C-N bond formation via allylic and aromatic C-H amination of α-methylstyrenes with diaziridinone.

ABSTRACT: A novel Pd(0)-catalyzed sequential C-N bond formation process via allylic and aromatic C-H amination of α-methylstyrenes with di-tert-butyldiaziridinone, giving spirocyclic indolines in good yields, is described. Four C-N bonds and one spiro quaternary carbon are generated in a single operation.

SUBMITTER: Ramirez TA 

PROVIDER: S-EPMC3864675 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature