The -159C/T polymorphism in the CD14 gene and cancer risk: a meta-analysis.

ABSTRACT:

Purpose

The -159C/T polymorphism in the cluster of differentiation (CD)14 gene has been extensively studied for an association with cancer; however, results from replication studies have been inconclusive. The aim of this study was to perform a comprehensive assessment of the possible association between the -159C/T polymorphism in the CD14 gene and cancer risk, by meta-analysis.

Methods

We searched in PubMed, Embase, and other databases, covering all case-control studies on the possible association between CD14 -159C/T gene polymorphism and cancer risk. Data were extracted and statistical analyses were performed using RevMan 5.0 and STATA 12.0 software.

Results

A total of 12 case-control studies met our inclusion criteria, including 2,498 cases and 2,696 controls. Th

SUBMITTER: Zhou W 

PROVIDER: S-EPMC3865088 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature