Markers of decongestion, dyspnea relief, and clinical outcomes among patients hospitalized with acute heart failure.

ABSTRACT:

Background

Congestion is a primary driver of symptoms in patients with acute heart failure, and relief of congestion is a critical goal of therapy. Monitoring of response to therapy through the assessment of daily weights and net fluid loss is the current standard of care, yet the relationship between commonly used markers of decongestion and both patient reported symptom relief and clinical outcomes are unknown.

Methods and results

We performed a retrospective analysis of the randomized clinical trial, diuretic optimization strategy evaluation in acute heart failure (DOSE-AHF), enrolling patients hospitalized with a diagnosis of acute decompensated heart failure. We assessed the relationship among 3 markers of decongestion at 72 hours-weight loss, net fluid loss, and percen

SUBMITTER: Kociol RD 

PROVIDER: S-EPMC3865520 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature