Ion channel models based on self-assembling cyclic peptide nanotubes.

ABSTRACT: The lipid bilayer membranes are Nature's dynamic structural motifs that individualize cells and keep ions, proteins, biopolymers and metabolites confined in the appropriate location. The compartmentalization and isolation of these molecules from the external media facilitate the sophisticated functions and connections between the different biological processes accomplished by living organisms. However, cells require assistance from minimal energy shortcuts for the transport of molecules across membranes so that they can interact with the exterior and regulate their internal environments. Ion channels and pores stand out from all other possible transport mechanisms due to their high selectivity and efficiency in discriminating and transporting ions or molecules across membrane barriers. Nev

SUBMITTER: Montenegro J 

PROVIDER: S-EPMC3867521 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature