Parameters for the mathematical modelling of Clostridium difficile acquisition and transmission: a systematic review.

ABSTRACT:

Introduction

Mathematical modelling of Clostridium difficile infection dynamics could contribute to the optimisation of strategies for its prevention and control. The objective of this systematic review was to summarise the available literature specifically identifying the quantitative parameters required for a compartmental mathematical model of Clostridium difficile transmission.

Methods

Six electronic healthcare databases were searched and all screening, data extraction and study quality assessments were undertaken in duplicate. Results were synthesised using a narrative approach.

Results

Fifty-four studies met the inclusion criteria. Reproduction numbers for hospital based epidemics were described in two studies with a range from 0.55 to 7. Two studies provided co

SUBMITTER: Otete EH 

PROVIDER: S-EPMC3869946 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature