Effects of Growth Hormone Administration on Muscle Strength in Men over 50 Years Old.

ABSTRACT: Growth hormone (GH) use has been speculated to improve physical capacity in subjects without GH deficiency (GHD) through stimulation of collagen synthesis in the tendon and skeletal muscle, which leads to better exercise training and increased muscle strength. In this context, the use of GH in healthy elderly should be an option for increasing muscle strength. Our aim was to evaluate the effect of GH therapy on muscle strength in healthy men over 50 years old. Fourteen healthy men aged 50-70 years were evaluated at baseline for body composition and muscle strength (evaluated by leg press and bench press exercises, which focus primarily on quadriceps-lower body part and pectoralis major-upper body part-muscles, resp.). Subjects were randomised into 2 groups: GH therapy (7 subjects) and plac

SUBMITTER: Tavares AB 

PROVIDER: S-EPMC3870652 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature