Differential adaptation to multi-stressed conditions of wine fermentation revealed by variations in yeast regulatory networks.

ABSTRACT:

Background

Variation of gene expression can lead to phenotypic variation and have therefore been assumed to contribute the diversity of wine yeast (Saccharomyces cerevisiae) properties. However, the molecular bases of this variation of gene expression are unknown. We addressed these questions by carrying out an integrated genetical-genomic study in fermentation conditions. We report here quantitative trait loci (QTL) mapping based on expression profiling in a segregating population generated by a cross between a derivative of the popular wine strain EC1118 and the laboratory strain S288c.

Results

Most of the fermentation traits studied appeared to be under multi-allelic control. We mapped five phenotypic QTLs and 1465 expression QTLs. Several expression QTLs overlapped in ho

SUBMITTER: Brion C 

PROVIDER: S-EPMC3870980 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature