Overlapping and divergent signaling pathways for ARK1 and AGD1 in the control of root hair polarity in Arabidopsis thaliana.

ABSTRACT: We previously showed that seedlings harboring mutations in genes encoding ARK1, an armadillo repeat-containing kinesin, or AGD1, a class 1 ARF-GAP, have root hairs that exhibit wavy/spiral growth and two tips originating from one initiation site. These root hair defects were accompanied by bundling of endoplasmic microtubules and filamentous actin (F-actin) that extended to the extreme root hair apex. The similar phenotypes of ark1 and agd1 mutants suggest a tight coordination between the cytoskeleton and membrane trafficking in the control of root hair polarity. Indeed, cell biological and genetic studies of the agd1 mutant provided evidence that AGD1's involvement in root hair development involves cross-talk among phosphoinositides (PIs), the actin cytoskeleton and other small GTPases su

SUBMITTER: Yoo CM 

PROVIDER: S-EPMC3871054 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature