Diamond-lipid hybrids enhance chemotherapeutic tolerance and mediate tumor regression.

ABSTRACT: Self-assembled nanodiamond-lipid hybrid particles (NDLPs) harness the potent interaction between the nanodiamond (ND)-surface and small molecules, while providing a mechanism for cell-targeted imaging and therapy of triple negative breast cancers. Epidermal growth factor receptor-targeted NDLPs are highly biocompatible particles that provide cell-specific imaging, promote tumor retention of ND-complexes, prevent epirubicin toxicities and mediate regression of triple negative breast cancers.

SUBMITTER: Moore LK 

PROVIDER: S-EPMC3872062 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature