Association of the frontal QRS-T angle with adverse cardiac remodeling, impaired left and right ventricular function, and worse outcomes in heart failure with preserved ejection fraction.

ABSTRACT:

Background

No prior studies have investigated the association of QRS-T angle with cardiac structure and function and outcomes in heart failure with preserved ejection fraction (HFpEF). The aim of this study was to test the hypothesis that increased frontal QRS-T angle is associated with worse cardiac function and remodeling and adverse outcomes in HFpEF.

Methods

A total of 376 patients with HFpEF (i.e., symptomatic heart failure with left ventricular ejection fraction > 50%) were prospectively studied. The frontal QRS-T angle was calculated from the 12-lead electrocardiogram. Patients were divided into tertiles by frontal QRS-T angle (0°-26°, 27°-75°, and 76°-179°), and clinical, laboratory, and echocardiographic data were compared among groups. Cox proportional-hazards anal

SUBMITTER: Selvaraj S 

PROVIDER: S-EPMC3872517 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature