Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor.

ABSTRACT: Rise and shine: Using a gene-targeting approach aimed at identifying potential L-threonine:uridine-5'-transaldolases that catalyze the formation of (5'S,6'S)-C-glycyluridine, a new bacterial translocase I inhibitor was discovered from an actinomycete following fermentation optimization.

SUBMITTER: Funabashi M 

PROVIDER: S-EPMC3873198 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature