Association of IL-8 (-251 a/t) gene polymorphism with clinical parameters and chronic periodontitis.

ABSTRACT:

Objective

To investigate the correlation between IL-8 (-251 A/T) gene polymorphism and susceptibility to chronic periodontitis as well as different clinical parameters and severity of the condition in patients referred to dental school, Shiraz University of Medical Sciences, Shiraz, Iran.

Materials and methods

In this randomized cross sectional study, 227 non-smoking patients with chronic periodontitis (test) and 40 healthy individuals (control) were enrolled in this experiment and the following clinical parameters were employed in the study: Periodontal Pocket Depth (PPD), Clinical Attachment Level (CAL) and Bone Loss (BL). All participants underwent the PCR (Polymerase Chain Reaction) test to detect 251 A/T Single Nucleotide Polymorphism of IL8 gene.

Results

No sign

SUBMITTER: Khosropanah H 

PROVIDER: S-EPMC3875505 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature