Association of Trichomonas vaginalis and cytological abnormalities of the cervix in low risk women.

ABSTRACT:

Objective

Is Trichomonas vaginalis (TV) an inducing factor for the development of (pre-)cancerous lesions of the cervix?

Design

Cross sectional study.

Setting

Screening healthy Belgian women with low infection risk.

Sample

63,251 consecutive liquid based cervical samples.

Methods

Real time quantitative PCR for presence of TV, 18 HPV types and Pap smear analysis of cytologic abnormalities.

Main outcome measures

Association of TV and HPV with cervix dysplasia.

Results

The overall prevalence of TV DNA was 0.37%, of low risk HPV 2%, of high risk HPV 13.2%, and 8.8 % had cytological abnormalities. Both LR-HPV and HR-HPV were significantly associated with all cytological abnormalities. Presence of TV was associated with LR- and HR-HPV, ASC-US and

SUBMITTER: Donders GG 

PROVIDER: S-EPMC3875579 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature