Ontology highlight
ABSTRACT:
SUBMITTER: Singh S
PROVIDER: S-EPMC3875630 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
ACS chemical biology 20130523 7
Sugar methyltransferases (MTs) are an important class of tailoring enzymes that catalyze the transfer of a methyl group from S-adenosyl-l-methionine to sugar-based N-, C- and O-nucleophiles. While sugar N- and C-MTs involved in natural product biosynthesis have been found to act on sugar nucleotide substrates prior to a subsequent glycosyltransferase reaction, corresponding sugar O-methylation reactions studied thus far occur after the glycosyltransfer reaction. Herein we report the first in vit ...[more]