Endocarditis with ruptured cerebral aneurysm caused by Cardiobacterium valvarum sp. nov.

ABSTRACT: A fastidious gram-negative bacterium was isolated from the blood of a 37-year-old man who had insidious endocarditis with a sudden rupture of a cerebral aneurysm. Characterization of the organism through phylogenetic and phenotypic analyses revealed a novel species of Cardiobacterium, for which the name Cardiobacterium valvarum sp. nov. is proposed. C. valvarum will supplement the current sole species Cardiobacterium hominis, a known cause of endocarditis. Surgeries and antibiotic treatment cured the patient's infection and associated complications. During cardiac surgery, a congenital bicuspid aortic valve was found to be the predisposing factor for his endocarditis.

SUBMITTER: Han XY 

PROVIDER: S-EPMC387565 | biostudies-literature | 2004 Apr

REPOSITORIES: biostudies-literature