Awake reactivation predicts memory in humans.

ABSTRACT: How are new experiences transformed into memories? Recent findings have shown that activation in brain regions involved in the initial task performance reemerges during postlearning rest, suggesting that "offline activity" might be important for this transformation. It is unclear, however, whether such offline activity indeed reflects reactivation of individual learning experiences, whether the amount of event-specific reactivation is directly related to later memory performance, and what brain regions support such event-specific reactivation. Here, we used functional magnetic resonance imaging to assess whether event-specific reactivation occurs spontaneously during an active, postlearning delay period in the human brain. Applying representational similarity analysis, we found that succes

SUBMITTER: Staresina BP 

PROVIDER: S-EPMC3876238 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature