Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones.

ABSTRACT: Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones are reported. The spiro[pyrazolin-3,3'-oxindole] products are formed in good yields (up to 98%) and high enantioselectivity (up to 99% ee).

SUBMITTER: Gerten AL 

PROVIDER: S-EPMC3876797 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature